Table 2 Performance comparison of reported TM antibodies
Hapten | Immunogen hapten | Antibody | IC50 (ng/mL) | CR with TYL |
|---|---|---|---|---|
TYL-CHO | TYL-CMO-BSA | mAb [15] | 9.6 | 204.25% |
TYL-CMO | TYL-CMO-BSA | mAb 2B3 [16] | 2.1 | 368.42% |
TM-H1 | OMT-H1-KLH | mAb Til-1 [17] | 48 | - |
mAb Til-2 [17] | 43.5 | - | ||
mAb Til-3 [17] | 54 | - | ||
mAb Til-4 [17] | 37.5 | - | ||
mAb Til-5 [17] | 32 | - | ||
mAb Til-6 [17] | 38 | - | ||
TM-H2 | TM-H1-BSA | mAb [18] | 1.40 | - |
TM-HS | TM-HS-KLH | mAb 12C8 [this work] | 0.36 | - |