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Fig. 3 | One Health Advances

Fig. 3

From: The replicase protein nsp2 of Chinese highly pathogenic porcine reproductive and respiratory virus is involved in protective immunity by promoting viral clearance

Fig. 3

The manifestations of piglets after immunization. A The rectal temperature curves of piglets after immunization and before challenge. B Clinical mental state scores of piglets inoculated with the rescued viruses. The total clinical scores were the sum of gross clinical score (GCS), respiratory clinical score (RCS), and nervous signs score (NSS). C The viremia of piglets inoculated with the rescued viruses after immunization and before challenge. Virus titers were determined by endpoint dilution assay in MARC-145 cells. Error bars represent standard deviation (SD). Asterisks mean the statistical difference between chimeric viruses and CHsx1401 (*, P < 0.05; **, P < 0.01; ***, P < 0.001)

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