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Fig. 2 | One Health Advances

Fig. 2

From: The replicase protein nsp2 of Chinese highly pathogenic porcine reproductive and respiratory virus is involved in protective immunity by promoting viral clearance

Fig. 2

Genetic variation of the PLP2 domain contributes to weak cross-neutralizing responses between heterologous strains. A Genomic organization and construction of chimeric PRRSV mutants. B IFA analysis of PRRSV mutants. MARC-145 cells in six-well plates were infected with the indicated viruses at an MOI of 0.1, fixed at 24 h post-infection (hpi), and then stained with mouse monoclonal antibody against PRRSV N protein. C–D Determination of NA titer of anti-JXwn06 hyper-immune serum against PRRSV mutants in MARC-145 cells. The error bars indicate means standard deviation (SD). Asterisks (*) indicate mean the statistical difference (*, P < 0.05; **, P < 0.01; ***, P < 0.001)

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One Health Advances

ISSN: 2731-9970

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