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Fig. 6 | One Health Advances

Fig. 6

From: A novel strategy to attenuate porcine reproductive and respiratory syndrome virus by inhibiting viral replication in the target pulmonary alveolar macrophages via hematopoietic-specific miR-142

Fig. 6

Characteristics of the RvJX-miR-142tM. (A) Sequences alignment of the miR-142 target sequence inserted region in PRRSV nsp2. The miR-142 target sequence is in the yellow box. Dashes indicate deleted amino acids compared to RvJX-miR-142t. (B) The growth kinetics of RvJX-miR-142tM. The data are shown as means ± SD (error bars). Asterisks indicate a significant difference in the virus titers between RvJX-miR-142t and RvJX-miR-142tM. (*, p < 0.05; ***, p < 0.001)

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